J. Jang, J. Kim, H.J. Lee, and J. H. Chang "Transrectal Ultrasound and Photoacoustic Imaging Probe for Diagnosis of Prostate Cancer," Sensors, 2021
S. Kang, J. Lee, and J. H. Chang, "Effectiveness of synthetic aperture focusing and coherence factor weighting for intravascular ultrasound imaging," Ultrasonics, vol. 113, 106364, 2021.
Y. Jang, H. Kim, S. Yoon, H. Lee, J. Hwang, J. Jung, J. H. Chang, J. Choi, and H. Kim, "Exosome-based photoacoustic imaging guided photodynamic and immunotherapy for the treatment of pancreatic cancer," J. Control. Release, vol. 330, pp. 293 - 304, 2021.
H. Kim, H. Lee, H. Kim and J. H. Chang, "Elimination of non-targeted photoacoustic signals for combined photoacoustic and ultrasound imaging," IEEE Trans. Ultrason., Ferroelectr., Freq. Control, 2021 (in press)
J. Kim, H. M. Lew, J. -H. Kim, S. Youn, H. A. Faruque, A. N. Seo, S. Y. Park, J. H. Chang, E. Kim, and J. Y. Hwang, "Forward-looking multimodal endoscopic system based on optical multispectral and high-frequency ultrasound imaging techniques for tumor detection," IEEE Trans. Med. Imaging, 2020 (in press).
J. Kim, H. Kim, and J. H. Chang, "Endoscopic probe for ultrasound-assisted photodynamic therapy of deep-lying tissue," IEEE Access, vol. 8, pp. 179745 – 179753, 2020.
S. Park, S. Kang, and J. H. Chang, "Optically transparent focused transducers for combined photoacoustic and ultrasound microscopy," J. Med. Biol. Eng., vol. 40, pp. 707 – 718, 2020.
C. Lee, J. Park, J. Lee, J. –I. Ha, H. Choi, and J. H. Chang, “Magnetically actuated forward-looking interventional ultrasound imaging: feasibility studies,” IEEE Trans. Biomed. Eng., vol. 67, no. 6, pp. 1797 – 1805, 2020.
T. Choi, H. Yu, S. Chang, D. –H. Ha, D. –W. Cho, J. Jang, C. Lee, G. Lu, J. H. Chang, Q. Zhou, J. Park, “Visibility of bioresorbable vascular scaffold in intravascular ultrasound imaging,” IEEE Trans. Ultrason., Ferroelectr., Freq. Control, vol. 67, no. 6, pp. 1090 – 1101, 2020.
H. Kim, H. Lee, H. Moon, J. Kang, Y. Kang, D. Kim, J. Kim, E. Huynh, G. Zheng, H. Kim, and J. H. Chang, “Resonance-based frequency-selective amplification for increased photoacoustic imaging sensitivity,” ACS Photonics, vol. 6, no. 9, pp. 2268 – 2276, 2019.
J. Lee and J. H. Chang, “Dual-element intravascular ultrasound transducer for tissue harmonic imaging and frequency compounding: development and imaging performance assessment,” IEEE Trans. Biomed. Eng., vol. 66, no. 11, pp. 3146 – 3155, 2019.
S. Youn, J. W. Choi, J. S. Lee, J. Kim, I. –H. Yang, J. H. Chang, H. C. Kim, and J. Y. Hwang, “Acoustic trapping technique for studying calcium response of a suspended breast cancer cell: determination of its invasion potentials,” IEEE Trans. Ultrason., Ferroelectr., Freq. Control, vol. 66, no. 4, pp. 737 – 746, 2019
J. Lee and J. H. Chang, “A 40-MHz ultrasound transducer with an angled aperture for guiding percutaneous revascularization of chronic total occlusion: a feasibility study,” Sensors, vol. 18, 4079, 2018.
J. Jang and J. H. Chang, “Design and fabrication of a miniaturized convex array for combined ultrasound and photoacoustic imaging of the prostate,” IEEE Trans. Ultrason., Ferroelectr., Freq. Control, vol. 65, no. 11, pp. 2086 – 2096, 2018.
E. –J. Shin, B. Kang, and J. H. Chang, “Real-time HIFU treatment monitoring using pulse inversion ultrasonic imaging,” Appl. Sci., vol. 8, no. 11, 2219, 2018.
J. Lee, E. –J. Shin, C. Lee, and J. H. Chang, “Development of dual-frequency oblong-shaped-focused transducers for intravascular ultrasound tissue harmonic imaging,” IEEE Trans. Ultrason., Ferroelectr., Freq. Control, vol. 65, no. 9, pp. 1571 – 1582, 2018.
H. Kim, G. Jo, and J. H. Chang, “Ultrasound-assisted photothermal therapy and real-time treatment monitoring,” Biomed. Opt. Express, vol. 9, no. 9, pp. 4472 – 4480, 2018.
J. Lee, J. –Y. Moon, and J. H. Chang, “A 35 MHz/105 MHz dual-element transducer for intravascular ultrasound tissue imaging using the third harmonic,” Sensors, vol. 18, no. 7, 2290, 2018.
H. Kim and J. H. Chang, “Multimodal photoacoustic imaging as a tool for sentinel lymph node identification and biopsy guidance,” Biomed. Eng. Lett., vol. 8, pp. 183 – 191, 2018.
S. Lee, H. Lee, H. Han, H. Yoo, H. Kim, J. H. Chang, and H. Kim, "External stimuli-responsive melanin-like nanoparticles for photoacoustic imaging-guided therapy," Sci. Adv. Mater., vol. 10, no. 7, pp. 665 – 673, 2018.
H. Kim and J. H. Chang, “Increased light penetration due to ultrasound-induced air bubbles in optical scattering media,” Sci. Rep., vol. 7, 16105, 2017. (selected as one of the top 100 read physics papers for Scientific Reports in 2017)
M. G. Kim, J. Park, H. G. Lim, S. Yoon, C. Lee, J. H. Chang, and K. K. Shung, “Label-free analysis of the characteristics of a single cell trapped by acoustic tweezers,” Sci. Rep., vol. 7, 14092, 2017.
J. Yu, J. Schuman, K. –J. Lee, S. G. Lee, J. H. Chang, and K. Kim, “A light illumination enhancement device for photoacoustic imaging: in vivo animal study,” IEEE Trans. Ultrason., Ferroelectr., Freq. Control, vol. 64, no. 8, pp. 1205 – 1211, 2017. (selected as a front cover image in the August issue, 2017)
H. D. Chae, J. Y. Lee, J. Y. Jang, J. H. Chang, J. Kang, M. J. Kang, and J. K. Han, "Photoacoustic imaging for differential diagnosis of benign polyps versus malignant polyps of the gallbladder: a preliminary study," Korean J. Radiol., vol. 18, no. 5, pp. 821 – 827, 2017.
J. Kang, J. H. Chang, S. M. Kim, H. J. Lee, H. Kim, B. Wilson, and T. –K. Song, “Real-time sentinel lymph node biopsy guidance using combined ultrasound, photoacoustic, fluorescence imaging: in vivo proof-of-principle and validation with nodal obstruction,” Sci. Rep., vol. 7, 45008, 2017.
H. Moon, H. Kim, C. Sim, H. Lee, J. H. Chang, H. J. Lee, and H. Kim, "Non-invasive tumor therapy by indocyanine green and paclitaxel doubly loaded nanoparticles using photoacoustic imaging," Sci. Adv. Mater., vol. 7, no. 7, pp. 1177 – 1186, 2017.
H. Moon, J. Kang, H. Lee, M. Lee, J. H. Chang, J. H. Lee, and H. Kim, "Theragnostic nanodroplets for photoacoustic and ultrasound signal amplification and optically triggered vaporization-induced drug release," J. Nanosci. Nanotechnol., vol. 17, no. 11, pp. 7978 - 7985, 2017.
H. Lee, H. Kim, H. Han, M. Lee, S. Lee, H. Yoo, J. H. Chang, and H. Kim, "Microbubbles used for contrast enhanced ultrasound and theragnosis: A review of principles to applications," Biomed. Eng. Lett., vol. 7, no. 2, pp. 59 - 69, 2017. (Best Paper Award)
J. Lee, J. Jang, and J. H. Chang, "Oblong-shaped-focused transducers for intravascular ultrasound imaging," IEEE Trans. Biomed. Eng., vol. 64, no. 3, pp. 671 – 680, 2017.
J. -Y. Moon, J. Lee, and J. H. Chang, "Electrical impedance matching networks based on filter structures for high frequency ultrasound transducers," Sens. Actuators A: Phys., vol. 251, pp. 225 - 233, 2016.
K. -Y. Ju, J. Kang, J. Pyo, J. Lim, J. H. Chang, and J. -K. Lee, "pH-induced aggregated melanin nanoparticles for photoacoustic signal amplification," Nanoscale, vol. 8, pp. 14448 - 14456, 2016.
H. Lee, H. Kim, T. P. Nguyen, J. H. Chang, S. Y. Kim, H. Kim, and E. Kang, "Nanocomposites of molybdenum disulfide/methoxy Polyethylene glycol-co-polypyrrole for amplified photoacoustic signal," ACS Appl. Mater. Interfaces, vol. 8, pp. 29213 - 29219, 2016.
J. Kim, H. Kim, H. Moon, H. Lee, J. H. Chang, J. Kim, and H. Kim, "Multifunctional theranostic nanomedicine for photoacoustic imaging-guided combination tumor treatment," J. Nanosci. Nanotechnol., vol. 16, pp. 11903 - 11910, 2016.
K. -Y. Ju, J. Kang, J. H. Chang, and J. -K. Lee, "Clue to understanding the Janus behavior of eumelanin: investigating the relationship between hierarchical assembly structure of eumelanin and its photophysical properties," Biomacromolecules, vol. 17, pp. 2860 - 2872, 2016.
J. Jang and J. H. Chang, "Design and fabrication of double-focused ultrasound transducers to achieve tight focusing," Sensors, vol. 16, 1248, 2016.
S. H. Kim and J. H. Chang, “Effect of the acoustic properties of lens materials on the performance of capacitive micromachined ultrasonic transducers,” J. Med. Biol. Eng., vol. 36, pp. 536 - 544, 2016.
J. Kang, C. Yoon, J. Lee, S. –B. Kye, Y. Lee, J. H. Chang, G. –D. Kim, Y. Yoo, and T. –K. Song, “A system-on-chip solution for point-of-care ultrasound imaging systems: architecture and ASIC implementation,” IEEE Trans. Biomed. Circuits Syst., vol. 10, no. 2, pp. 412 – 423, 2016.
J. H. Cha, B. Kang, J. Jang, and J. H. Chan, “A 15-MHz 1-3 piezocomposite concave array transducer for ophthalmic imaging,” IEEE Trans. Ultrason., Ferroelectr., Freq. Control, vol. 62, no. 11, pp. 1994 – 2004, 2015. (selected as a front cover image in the November issue, 2015)
H. Moon, J. Kang, C. Sim, J. Kim, H. Lee, J. H. Chang, and H. Kim, “Multifunctional theranostic contrast agent for photoacoustic- and ultrasound-based tumor diagnosis and ultrasound-stimulated local tumor therapy,” J. Control. Release, vol. 218, pp. 63 – 71, 2015.
H. Moon, C. Yoon, T. W. Lee, K. –S. Ha, J. H. Chang, T. –K. Song, K. Kim, and H. Kim, “Therapeutic ultrasound contrast agents for the enhancement of tumor diagnosis and tumor therapy,” J. Biomd. Nanotechnol., vol. 11, no. 7, pp. 1183-1192, 2015.
H. Moon, D. Kumar, H. Kim, C. Sim, J. H. Chang, J. -M. Kim, H. Kim, and D. -K. Lim, "Amplified photoacoustic performance and enhanced photothermal stability of reduced graphene oxide-coated gold nanorods for sensitive photoacoustic imaging," ACS Nano, vol. 9, no. 3, pp. 2711-2719, 2015.
B. L. Yun, S. M. Kim, M. Jang, H. S. Ahn, C. Y. Lyou, M. S. Kim, S. A. Kim, T. -K. Song, Y. Yoo, J. H. Chang, and, Y. Kim, "Does adding diffuse optical tomography to US improve the differentiation between benign and malignant breast lesions?,"
J. Ultras. Med., vol. 34, no. 5, pp. 749-757, 2015.
S. H. Lee, S. M. Kim, M. Jang, B. L. Yun, E. Kang, S. W. Kim, S. Y. Park, H. S. Ahn, J. H. Chang, Y. Yoo, T. -K. Song, W. K. Moon, "Role of second-look ultrasound examinations for MR-detected lesions in patients with breast cancer," Ultraschall in Med., vol. 36, pp. 140-148, 2015.
J. Kang, J. H. Chang, B. Wilson, I. Veileux, Y. Bai, R. DaCosta, K. Kim, S. Ha, J. G. Lee, J. S. Kim, S. –G. Lee, S. M. Kim, H. J. Lee, Y. B. Ahn, S. Han, Y. Yoo, and T. –K. Song, “A prototype hand-held tri-modal instrument for in vivo ultrasound, photoacoustic, fluorescence imaging,” Rev. Sci. Instrum., vol. 86, 034901, 2015.
C. Sim, H. Kim, H. Moon, H. Lee, J. H. Chang, and H. Kim, "Photoacoustic-based nanomedicine for cancer diagnosis and therapy," J. Control. Release, vol. 203, pp. 118 - 125, 2015.
J. Kang, E. -K. Kim, G. R. Kim, C. Yoon, T. -K. Song, and J. H. Chang, "Photoacoustic imaging of breast microcalcifications: a validation study with 3-dimensional ex vivo data and spectrophotometric measurement," J. Biophotonics, vol. 8, pp. 71-80, 2015.
J. Kang, W. Y. Chung, S. –W. Kang, H. J. Kwon, J. Yoo, E. –K. Kim, J. H. Chang, T. –K. Song, S. Lee, and J. Y. Kwak, “Ex vivo estimation of photoacoustic imaging for detecting thyroid microcalcifications,” PLoS One, vol. 9, no. 11, e113358, 2014.
G. R. Kim, J. Kang, J. Y. Kwak, J. H. Chang, S. I. Kim, J. H. Youk, H. J. Moon, M. J. Kim, and E. –K. Kim, “Photoacoustic imaging of breast microcalcifications: a preliminary study with 8-gauge core-biopsied breast specimens,” PLoS One, vol. 9, no. 8, e105878, 2014.
J. H. Cha and J. H. Chang, "Development of 15 MHz 2-2 piezo-composite ultrasound linear array transducers for ophthalmic imaging," Sensor. Actuat. A-Phys., vol. 217, pp. 39-48, 2014.
J. H. Song and J. H. Chang, "An effective pulse sequence for simultaneous HIFU insonation and monitoring," IEEE Trans. Ultrason., Ferroelectr., Freq. Control, vol. 61, no. 9, pp. 1580 – 1587, 2014
C. Yoon, Y. Yoo, T. -K. Song, and J. H. Chang, "Pixel based focusing for photoacoustic and ultrasound dual-modality imaging," Ultrasonics, vol. 54, pp. 2126 – 2133, 2014.
H. Kim, J. Kang, and J. H. Chang, "Thermal therapeutic method for selective treatment of deep-lying tissue by combining laser and high-intensity focused ultrasound energy," Opt. Lett., vol. 39, no. 9, pp. 2806 – 2809, 2014.
J. Park, J. B. Kang, J. H. Chang, and Y. Yoo, "Speckle reduction techniques in medical ultrasound imaging," Biomed. Eng. Lett., vol. 4, pp. 32 – 40, 2014.
J. H. Song, Y. Yoo, T. -K. Song, and J. H. Chang, "Real-time monitoring of HIFU treatment using pulse inversion," Phys. Med. Biol., vol. 58, pp. 5333 – 5350, 2013.
C. Yoon, G. -D. Kim, Y. Yoo, T. -K. Song, and J. H. Chang, "Frequency equalized compounding for effective speckle reduction in medical ultrasound imaging," Biomed. Signal Process. Control, vol. 8, pp. 876 – 887, 2013.
C. Yoon, W. Y. Lee, J. H. Chang, T. -K. Song, and Y. Yoo, "An efficient pulse compression method of chirp coded excitation in medical ultrasound imaging," IEEE Trans. Ultrason., Ferroelectr., Freq. Control, vol. 60, no. 10, pp. 2225 – 2229, 2013.
H. Moon, J. Yu, S. Park, J. H. Chang, T. –K. Song, and H. Kim, “Narrow size distribution of microbubbles for enhancement of harmonic imaging,” J. Biomed. Nanotechnol., vol. 9, no. 5, pp. 845 – 848, 2013
J. S. Jeong, J. H. Chang, and K. K. Shung, “Pulse compression technique for simultaneous HIFU surgery and ultrasonic imaging: a preliminary study,” Ultrasonics, vol. 52, pp. 730 – 739, 2012.
C. Yoon, H. Seo, Y. Lee, Y. Yoo, T. –K, Song, and J. H. Chang, “Optimal sound speed estimation using modified nonlinear anisotropic diffusion to improve spatial resolution in ultrasound imaging,” IEEE Trans. Ultrason., Ferroelectr., Freq. Control, vol. 59, no. 5, pp. 905 – 014, 2012.
C. Yoon, Y. Yoo, T. –K, Song, and J. H. Chang, “Orthogonal quadratic chirp signals for simultaneous multi-zone focusing in medical ultrasound imaging,” IEEE Trans. Ultrason., Ferroelectr., Freq. Control, vol. 59, no. 5, pp. 1061 – 1069, 2012.
Y. Lee, W. Y. Lee, C. –E. Lim, J. H. Chang, T. –K. Song, and Y. Yoo, “Compounded direct pixel beamforming for medical ultrasound imaging,” IEEE Trans. Ultrason., Ferroelectr., Freq. Control, vol. 59, no. 3, pp. 573 – 882, 2012.
D. –Y. Lee, Y. Yoo, T. –K. Song, and J. H. Chang, “Adaptive dynamic quadrature demodulation with autoregressive spectral estimation in ultrasound imaging,” Biomed. Signal Process. Control, vol. 7, no. 4, pp. 371 – 378, 2012.
C. Yoon, J. Kang, S. Han, Y. Yoo, T. –K. Song, and J. H. Chang, “Enhancement of photoacoustic image quality by sound speed correction: ex vivo evaluation,” Opt. Express, vol. 20, no. 3, pp. 3082 – 3090, 2012.
J. Kang, E. –K. Kim, J. Y. Kwak, Y. Yoo, T. –K. Song, and J. H. Chang, “Optimal laser wavelength for photoacoustic imaging of breast microcalcifications,” Appl. Phys. Lett., vol. 99, 153702, 2011.
J. Lee, J. H. Chang, J. S. Jeong, C. Lee, S. -Y. Teh, A. Lee, and K. K. Shung, "Backscattering measurement from a single microdroplet," IEEE Trans. Ultrason., Ferroelectr., Freq. Control, vol. 58, no. 4, pp. 874 – 879, 2011.
C. Yoon, Y. Lee, J. H. Chang, Y. Yoo, and T. -K. Song, "In vitro estimation of mean sound speed based on minimum average phase variance in medical ultrasound imaging," Ultrasonics, vol. 51, pp. 795 – 802, 2011.
J. H. Chang, "A new approach to ophthalmic imaging with concave array transducers," Biomed. Eng. Lett., vo. 1, pp. 62 - 67, 2011.
J. Song, J. H. Chang, T. -K Song, and Y. Yoo, "Coded tissue harmonic imaging with nonlinear chirp signals," Ultrasonics, vol. 51, 516 - 521, 2011.
J. H. Chang and T. -K Song, "A new synthetic aperture focusing method to suppress the diffraction of ultrasound," IEEE Trans. Ultrason., Ferroelectr., Freq. Control, vol. 58, no. 2, pp. 327 - 337, 2011.
J. H. Chang, D. T. Raphael, Y. Zhang, and K. K. Shung, "Proof of concept: in vitro measurement of correlation between radiodensity and ultrasound echo response of ovine vertebral bodies," Ultrasonics, vol. 51, pp. 253 - 257, 2011.
D. T. Raphael, J. H. Chang, Y. P. Zhang, D. Kudija, T. C. Chen, and K. K. Shung, "A-mode ultrasound guidance for pedicle screw advancement in ovine vertebral bodies," The Spine Journal, vol. 10, pp. 422 – 432, 2010.
J. H. Chang, H. H. Kim, J. Lee, and K. K. Shung, “Frequency Compounded Imaging with a High-Frequency Dual Element Transducer,” Ultrasonics, vol. 50, pp. 453 – 457, 2010.
J. S. Jeong, J. H. Chang, and K. K. Shung, “Ultrasound Transducer and System for Real-Time Simultaneous Therapy and Diagnosis for Noninvasive Surgery of Prostate Tissue,” IEEE Trans. Ultrason., Ferroelectr., Freq. Control, vol. 56, no. 9, pp. 1913 – 1922, 2009.
J. H. Chang, L. Sun, J. T. Yen, and K. K. Shung, “Low-Cost, High-Speed Back-End Processing System for High-Frequency Ultrasound B-Mode Imaging,” IEEE Trans. Ultrason., Ferroelectr., Freq. Control, vol. 56, no. 7, pp. 1490 – 1497, 2009.
D. –G. Paeng, J. H. Chang, R. Chen, M. S. Humayun, and K. K. Shung, “Feasibility of Rotational Scan Ultrasound Imaging by an Angled High Frequency Transducer for the Posterior Segment of the Eye,” IEEE Trans. Ultrason., Ferroelectr., Freq. Control, vol. 56, no. 3, pp. 676 – 680, 2009.
H. H. Kim, J. M. Cannata, R. Liu, J. H. Chang, R. H. Silverman, and K. K. Shung, “20 MHz / 40 MHz Dual Element Transducers for High Frequency Harmonic Imaging,” IEEE Trans. Ultrason., Ferroelectr., Freq. Control, vol. 55, no. 12, pp. 2683 – 2691, 2008.
J. H. Chang, J. T. Yen, and K. K. Shung, “High-Speed Digital Scan Converter for High-Frequency Ultrasound Sector Scanners,” Ultrasonics, vol. 48, pp. 444 – 452, 2008.
J. H. Chang, J. T. Yen, and K. K. Shung, “A Novel Envelope Detector for High-Frame Rate, High-Frequency Ultrasound Imaging,” IEEE Trans. Ultrason., Ferroelectr., Freq. Control, vol. 54, no. 9, pp. 1792 – 1801, 2007.